SI Joint Fusion for Low Back Pain: A Systematic Review & Meta-Analysis | SI-BONE

Clinical Data

Systematic Review & Meta-Analysis (Lingutla - Eur Spine J 2016)

Sacroiliac Joint Fusion for Low Back Pain: A Systematic Review and Meta-Analysis

Lingutla KK, Pollock R, Ahuja S.
Eur Spine J. 2016 Jun;25(6):1924-31. [Epub 2016 Mar 8].
DOI: 10.1007/s00586-016-4490-8

ABSTRACT

Background Context: Although pain is generally regarded as originating in the lumbar spine, it has been estimated that in 15-30 % of patients, LBP originates from the sacroiliac joint (SIJ).

Purpose: To determine whether sacroiliac joint fusion (SIJF) for LBP is effective in reducing pain when the SIJ is known to be the pain generator.

Study Design/Setting: Systematic review and meta-analysis.

Methods: A systematic literature review and meta-analysis was performed of observational studies describing outcome of SIJF in patients with LBP. Outcome measures were VAS pain, ODI, SF-36 PCS/MCS and Majeed score. The following databases were searched: PubMed, Web of Science, Embase, Medline and Google scholar. The methodological quality of selected studies was assessed using the National Heart Lung and Blood Institute case series quality assessment tool. Meta-analysis was used to combine the studies for each outcome and forest plots were prepared. Outcomes were expressed as mean difference (MD).

Results: Six studies were included in the meta-analysis with a mean follow-up of 17.6 months. All outcomes showed statistical and clinical improvement (VAS pain MD: 54.8; 95% CI 48.6, 61.0; n=380; p<0.001, ODI MD: 14.5; 95% CI 8.4, 20.6; n=102; p<0.001, SF-36 PCS MD: -19.5; 95% CI -24.7, -14.2; n=140; p<0.001, SF-36 MCS MD: -8.5; 95% CI -12.9, -4.1; n=198; p<0.001 and Majeed score MD: -35.4; 95% CI -48.5, -22.2; n=140; p<0.001).

Conclusions: SIJF appears to be a satisfactory procedure for alleviating pelvic girdle pain.

KEYWORDS: Fusion; Low back pain; Meta-analysis; Outcome; Pelvic girdle pain; Sacroiliac joint

Author Information

Lingutla KK and Ahuja S - Welsh Centre for Spinal Trauma and Surgery, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN, Wales, UK.

Pollock R - Welsh Centre for Spinal Trauma and Surgery, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN, Wales, UK. ray@pollock.org.uk.

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