Meet SI-BONE | Company Overview | SI-BONE


Advancing the diagnostic understanding of the sacroiliac joint and minimally invasive surgery for certain causes of SI joint disorders.

SI-BONE® was founded in April 2008, as a spin out when Wright Medical bought INBONE Technologies. INBONE, with the ENDO-FUSETM Intra-Osseous Fusion System, was founded by Dr. Mark Reiley, the inventor of kyphoplasty and the vertebral fracture treatment.



SI-BONE has developed an innovative, patented implant for some causes of SI joint pain. The iFuse Implant System® provides a less invasive alternative to traditional sacroiliac (SI) joint fusion surgery. The iFuse Implant System uses the same titanium implant technology that has been used in the ENDO-FUSE System. To date, more than 50,000 minimally invasive surgical SI joint fusions have been performed with the iFuse Implant System by more than 2,000 surgeons worldwide.

SI-BONE is managed by an experienced team of executives from Kyphon, Medtronic, INBONE, Saint Francis and several start-up orthopedic and spine companies.


According to the National Institute of Neurological Disorders and Stroke (a division of NIH), "Americans spend at least $50 billion each year on low back pain." Low back pain is the most common cause of job-related disability and a leading contributor to missed work. Several leading orthopedic publications over the last few years have stated that anywhere from 15-30% of all low back pain is SI joint in origin.1,2,3,4,5

According to a study by Bernard and Kirkaldy-Willis, over twenty two percent (22%) of individuals who presented with lower back pain actually had sacroiliac (SI) joint pain.1 A wealth of published clinical literature indicates that sacroiliac (SI) joint pain frequently mimics discogenic or radicular low back pain, resulting in many patients receiving lumbar fusion instead of sacroiliac (SI) joint fusion.26

SI-BONE is focused on helping patients in one of the most under-served, under-diagnosed, and under-treated areas in orthopedics, the sacroiliac (SI) joint. The iFuse Implant System is intended for sacroiliac fusion for conditions including sacroiliac joint dysfunction that is a direct result of sacroiliac joint disruption and degenerative sacroiliitis. This includes conditions whose symptoms began during pregnancy or in the peripartum period and have persisted postpartum for more than 6 months. The iFuse Implant System is also intended for sacroiliac fusion to augment immobilization and stabilization of the sacroiliac joint in skeletally mature patients undergoing sacropelvic fixation as a part of a lumbar or thoracolumbar fusion.

SI-BONE is a proud member of the following organizations:

MDMA logo AdvaMed logo Code of Ethics logo

2,400+Treating Surgeons

55,000+iFuse Procedures Performed

100+iFuse Publications

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