Systematic Review, MIS SI Joint Fusion | SI-BONE

Clinical Data

Systematic Review, MIS SI Joint Fusion (Heiney - IJSS 2015)

A Systematic Review of Minimally Invasive Sacroiliac Joint Fusion Utilizing A Lateral Transarticular Technique

Heiney J, Capobianco R, Cher D.
Int J Spine Surg. 2015 Jul 22;9:40. DOI: 10.14444/2040. PMCID: PMC4528567


Background: A number of studies have been published regarding minimally invasive surgical (MIS) fusion of the sacroiliac (SI) joint using a lateral transarticular approach. Herein we report a systematic review and meta-analysis to summarize operative measures and clinical outcomes reported in published studies of MIS SI joint fusion.

Methods: The systematic review was done according to PRISMA standards. PubMed and EMBASE were searched using the terms sacroiliac joint AND fusion. Original peer-reviewed articles in the English language that reported clinical outcomes on at least 5 cases of MIS SI joint fusion using a lateral transarticular approach were included. Random effects meta-analysis (RMA) was performed on selected variables using the DerSimonian and Laird method, including operative measures, VAS SI joint pain ratings (0-10 scale) and Oswestry Disability Index (ODI). Mean and 95% confidence intervals (CI) were calculated and heterogeneity was assessed. Other findings were summarized qualitatively.

Results: A total of 18 articles met the inclusion criteria. After accounting for overlapping cohorts, 12 unique cohorts from 4 countries were extracted for a total of 432 subjects. The RMA mean (range) was 59 minutes (27-78) for procedure time, 36.9cc (10-70) for estimated blood loss and 1.7 days (range 0-7) for length of stay (LOS). The RMA mean [95% CI] pain score dropped by 5.2 points at 6 months and 5.3 points at 12 months (baseline score of 8.1 [7.8-8.4], 12-month score of 2.7 [2.1-3.3]), and a 24-month score of 2.0(1.4-2.5). ODI decreased by 31 points at 12 months (baseline score of 56.2 [51.0-61.5], 6-month score of 30.7 [21.8-39.6], and 12-month score of 25.1 [12.3-37.9]). Some estimates showed significant variation across studies and between the types of implants used. Other reported outcomes were supportive of the positive effects of SI joint fusion.

Conclusion: Published studies of MIS SI joint fusion using a lateral transarticular approach confirm its minimally invasive characteristics with minimal blood loss and short operating room times, and show consistent, rapid, sustained and clinically important improvements in patient reported SI joint pain, disability and quality of life scores.


Jake Heiney, MD,1 Robyn Capobianco, MA,2 Daniel Cher, MD2

1 University of Toledo Medical Center, Toledo, Ohio,
2 SI-BONE, Inc., San Jose, California

One or more of the individuals named herein may be a past or present SI-BONE employee, paid consultant, investor, clinical trial investigator, or grant recipient. Research described herein may have been supported in whole or in part by SI-BONE.

3,700+Treating Surgeons

100,000+iFuse Procedures Performed

130+iFuse Publications

Looking for Answers?

We can help. Tell us what you're looking for below.